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项光新 |
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教授,博士,硕士生导师 E-mail: 527619706@qq.com |
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个人简介:
项光新,教授,博士,浙江省医学会精准医学分会常委和医学遗传学分会委员。博士毕业于清华大学医学院,曾担任企业研发团队负责人并兼任国家“2011计划”感染性疾病诊治协同创新中心研究员,目前专注于高通量测序技术的临床诊断应用。
研究方向:
分子诊断技术的研发与临床应用。
招生信息:
医学技术、生物学。
科研成果:
曾主持国家科技重大专项课题1项,主持国家国际科技合作专项课题1项,承担国家863计划重大专项子课题1项,正在主持人才科研课题1项(经费100万元)和横向课题1项(经费80万元)。学术成果包括发表SCI论文20余篇,授权发明专利20余项,获批国家标准2项和国家卫计委技术规范1项;转化成果包括分子诊断产品获得国家药监局III类IVD注册证10项。获得国家技术发明奖二等奖、全国妇幼健康科技奖、中国专利优秀奖、黄家驷生物医学工程奖、中华医学科技奖等荣誉。
代表性论文:
1. Fang YY, Pei SJ, Huang KZ, Xu F, Xiang GX, Lan LH, Zheng XQ. Single-cell transcriptome reveals the metabolic and clinical features of a highly malignant cell subpopulation in pancreatic ductal adenocarcinoma. Frontiers in Cell and Developmental Biology, 10: 798165, 2022.
2. Yan D†, Xiang GX†, Chai XP, Qing J, Shang HQ, Zou B, Mittal R, Shen J, Smith RJ, Fan YS, Blanton SH, Tekin M, Morton C, Xing WL, Cheng J and Liu XZ. Screening of deafness-causing DNA variants that are common in patients of European ancestry using a microarray-based approach. PLoS ONE, 12: e0169219, 2017. †Co-first authors.
3. Huang SS†, Xiang GX†, Kang DY, Wang C, Kong YL, Zhang X, Liang SJ, Mitchelson K, Xing WL and Dai P. Rapid identification of aminoglycoside-induced deafness gene mutations using multiplex real-time polymerase chain reaction. International Journal of Pediatric Otorhinolaryngology, 79: 1067-1072, 2015. †Co-first authors.
4. Xiang GX, Pan LB, Xing WL, Zhang L, Huang LH, Yu J, Zhang R, Wu JP, Cheng J and Zhou YX. Identification of activity-dependent gene expression profiles reveals specific subsets of genes induced by different routes of Ca2+ entry in cultured rat cortical neurons. Journal of Cellular Physiology, 212: 126-136, 2007.
5. Xiang GX, Pan LB, Huang LH, Yu ZY, Song XD, Cheng J, Xing WL and Zhou YX. Microelectrode array-based system for neuropharmacological applications with cortical neurons cultured in vitro. Biosensors and Bioelectronics, 22: 2478-2484, 2007.
代表性专利:
1. 项光新、郑晓群、唐晨、徐峰,一种检测结核分枝杆菌耐药基因的引物组合及试剂盒,2022111400271。
2. 项光新、王璨、邢婉丽、程京,检测呼吸道感染相关病原微生物的系统及其专用LAMP引物,201510230691.9。
3. 项光新、梁书剑、邢婉丽,用于检测华法林与氯吡格雷个体化用药相关基因的多态性的试剂盒及其应用,2014101806994。