方合志，博士，教授，硕士导师，中华医学会浙江省医学遗传学分会青年委员会副主任委员、中国医师协会检验医师分会线粒体疾病医学检验专业委员会委员。长期致力于线粒体遗传病相关致病基因及突变的发现和功能鉴定以及线粒体基因组多态性协同核基因表达变化在退行性疾病发生中的作用研究。主持多项国家级课题，围绕线粒体共发表SCI论著27篇，其中以第一作者或通讯作者在Diabetes, Int J Cancer，Biochim Biophys Acta-Mol.Basis.Dis，Cell Death Dis等杂志上发表论文多篇。

发表文章（* 通讯作者， # 第一作者）

1.Fang Hezhi#*, Hu Nianqi#, Zhao Qiongya#, Wang Bingqian#, Zhou Huaibin, Fu Qingzi, Shen Lijun, Chen Xiong, Shen Feixia, Lyu Jianxin*. mtDNA Haplogroup N9a Increases the Risk of T2DM by Altering Mitochondrial Function and Intracellular Mitochondrial Signals. Diabetes. 2018 May 7.

2. Zhou Chao#, Sun Hongwei#, Zheng Chen#, Gao Jing, Fu Qingzi, Hu Nianqi, Shao Xiaoli, Zhou Yingying, Xiong Jingting, Nie Ke, Zhou Huaibin, Shen Lijun, Fang Hezhi*, Lyu Jianxin*. Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2activation during pancreatic cancer cell growth. Cell Death Dis 2018 Feb 07;9 (2)

3.Ma Lin#, Fu Qingzi#, Xu Bing#, Zhou Huaibin, Gao Jing, Shao Xiaoli, Xiong Jingting, Gu Qianru, Wen Shumeng, Li Fengjie, Shen Lijun, Chen Guorong*, Fang Hezhi*, Lyu Jianxin. Breast cancer-associated mitochondrial DNA haplogroup promotes neoplastic growth via ROS-mediated AKT activation. Int J Cancer. 2018 May 1;142(9):1786-1796c

招生信息：

临床检验诊断学、医学技术、生物学