| 包其郁 |
| 教授,博士生导师 E-mail: baoqywzmc@aliyun.com |
|
包其郁,享受国务院政府特殊津贴,温州市高层次人才,温州市新世纪551工程第一层次人才,2014年被评为浙江省省级优秀教师,2012年被评为浙江省卫生厅先进工作者,并多次被评为温州医学院先进工作者和优秀带教老师。中国遗传学会微生物遗传专业委员会委员、浙江省生物化学与分子生物学学会理事、浙江省遗传学会理事、《遗传》杂志编委会编委。
在教学方面,曾执教《医学微生物学》、《免疫学》、《微生物学》、《生物信息与数据处理》、《生物化学》和《法医物证学》的教学工作。除上好本科生的理论课教学外,还培养了硕士研究生、博士研究生50多位,并指导、带领大学生参加浙江省、全国大学生生命科学竞赛和挑战杯赛,多次获得各类比赛的一、二等奖。
在学科建设方面,开设信息与数据处理理论和实验课;建立生物信息学研究平台。在科研方面,曾参加人类基因组计划和水稻基因组计划;现带领的科研团队利用基因组、转录组、蛋白组技术和功能基因研究技术进行病原微生物的致病机理、耐药机理研究;进行螺旋藻抗逆的分子机理及功能基因研究;腾冲嗜热厌氧菌的耐热机制和厌氧硫呼吸机理研究。承担国家自然科学基金项目和省部级科研基金项目各三项;发表SCI收录论著100多篇;先后获“中国科学院院长特别奖”、浙江省科技进步奖三等奖5项、温州市科技进步奖4项。
承担课题:
1. 携带新抗性基因铜绿假单胞菌的高水平多重耐药形成机制研究,浙江省自然科学基金面上项目, 2019.01-2021.12,项目负责人,已结题。
2. 铜绿假单胞菌抗药相关膜转运蛋白AmpG的构效关系研究,浙江省自然科学基金面上项目, 2014.01-2016.12,项目负责人。
3. 病原菌抗β-内酰胺类药物高度相关膜转运蛋白AmpG阻遏物的筛选, 卫生部,2013.01-2015.12,项目负责人。
4. 高通量测序分析病原菌质粒携带的耐药新基因, 81171614, 国家自然科学基金项目,2012.1-2015.12,第二。
5. 螺旋藻功能基因组及抗盐碱功能相关基因的研究,浙江省自然科学基金,2008.1-2010.12,项目负责人,已结题。
6. 疾病相关细菌耐药性基因检测芯片的制备,浙江省科技厅科技计划项目,2008.1-2010.12, 项目负责人,已结题。
7. 人体内和细胞传代培养SARS病毒基因组的遗传变异研究,C011003,国家自然科学基金项目,2007.1-2007.12,项目负责人,已结题。
8. 螺旋藻全基因生物信息分析,30571009,国家自然科学基金项目,2006.1-2008.12,项目负责人,已结题。
9. 业微生物杀虫防病功能基因的发掘和分子机理研究,2003CB114200,国家973计划课题,2004.11-2008.12,第二,已结题。
发表文章(* 通讯作者, # 第一作者)
1. Qiyu Bao, Yuqing Tian, Wei Li, Huanming Yang*, et al. A Complete Sequence of the T.tengcongensis Genome. Genome Research, 2002, 12(5): 689-700. (IF: 10.1)
2. Sheng X, Lu W, Li A, Lu J, Song C, Xu J, Dong Y, Fu C, Lin X, Zhu M, Bao Q, Li K*. ANT(9)-Ic, a Novel Chromosomally Encoded Aminoglycoside nucleotidyltransferase from Brucella intermedia. Microbiol Spectr. 2023 Apr 11:e0062023. doi: 10.1128/spectrum.00620-23. Online ahead of print.
3. Shi W, Lu J, Feng C, Gao M, Li A, Liu S, Zhang L, Zhang X, Li Q, Lin H, Lin X, Li K, Zhang H, Hu Y, Wang G, Bao Q*, Jiang W*. Functional characterization of a novel aminoglycoside phosphotransferase, APH(9)-Ic, and its variant from Stenotrophomonas maltophilia. Front Cell Infect Microbiol. 2023 Jan 9;12:1097561. doi: 10.3389/fcimb.2022.1097561. eCollection 2022.
4. Wang L, Zhu M, Yan C, Zhang Y, He X, Wu L, Xu J, Lu J, Bao Q, Hu Y*, Xu T*, Liang J*. Class 1 integrons and multiple mobile genetic elements in clinical isolates of the Klebsiella pneumoniae complex from a tertiary hospital in eastern China. Front Microbiol. 2023 Mar 6;14:985102. doi: 10.3389/fmicb. 2023.985102. eCollection 2023.
5. Liu S, Zhang L, Feng C, Zhu J, Li A, Zhao J, Zhang Y, Gao M, Shi W, Li Q, Zhang X, Zhang H, Xu T, Lu J, Bao Q*. Characterization and Identification of a novel chromosome-encoded metallo-β-lactamase WUS-1 in Myroides albus P34. Front Microbiol. 2022 Dec 1;13:1059997. doi: 10.3389/fmicb.2022.1059997. eCollection 2022.
6. Dong X, Zhu M, Li Y, Huang D, Wang L, Yan C, Zhang L, Dong F, Lu J, Lin X, Li K, Bao Q, Cong C*, Pan W*. Whole-Genome Sequencing-Based Species Classification, Multilocus Sequence Typing, and Antimicrobial Resistance Mechanism Analysis of the Enterobacter cloacae Complex in Southern China. Microbiol Spectr. 2022 Nov 9:e0216022. doi: 10.1128/spectrum.02160-22. Online ahead of print.
7. Gao M, Feng C, Ji Y, Shi Y, Shi W, Zhang L, Liu S, Li A, Zhang X, Li Q, Lu J, Bao Q*, Zhang H*. AadA36, a novel chromosomal aminoglycoside nucleotidyltransferase from a clinical isolate of Providencia stuartii. Front Microbiol. 2022 Nov 1;13:1035651. doi: 10.3389/fmicb.2022.1035651. eCollection 2022.
8. Feng C, Gao M, Jiang W, Shi W, Li A, Liu S, Zhang L, Zhang X, Li Q, Lin H, Lu J, Li K, Zhang H, Hu Y, Bao Q*, Lin X*. Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola. Front Microbiol. 2022 Sep 13;13:990739. doi: 10.3389/fmicb.2022.990739. eCollection 2022.
9. Lin H, Feng C, Zhu T, Li A, Liu S, Zhang L, Li Q, Zhang X, Lin L, Lu J, Lin X, Li K, Zhang H, Xu T, Li C, Bao Q*. Molecular Mechanism of the β-Lactamase Mediated β-Lactam Antibiotic Resistance of Pseudomonas aeruginosa Isolated From a Chinese Teaching Hospital. Front Microbiol. 2022 Apr 28;13:855961. doi: 10.3389/fmicb.2022.855961. eCollection 2022.
10. Li Q, Qian C, Zhang X, Zhu T, Shi W, Gao M, Feng C, Xu M, Lin H, Lin L, Lu J, Lin X, Li K, Xu T, Bao Q*, Li C*, Zhang H*. Colistin Resistance and Molecular Characterization of the Genomes of mcr-1-Positive Escherichia coli Clinical Isolates. Front Cell Infect Microbiol. 2022 May 6;12:854534. doi: 10.3389/fcimb.2022.854534. eCollection 2022.
11. Li P, Gao M, Feng C, Yan T, Sheng Z, Shi W, Liu S, Zhang L, Li A, Lu J, Lin X, Li K, Xu T, Bao Q*, Sun C*. Molecular characterization of florfenicol and oxazolidinone resistance in Enterococcus isolates from animals in China. Front Microbiol. 2022 Jul 26;13:811692. doi: 10.3389/fmicb.2022.811692. eCollection 2022.
12. Lin H, Feng C, Zhu T, Li A, Liu S, Zhang L, Li Q, Zhang X, Lin L, Lu J, Lin X, Li K, Zhang H, Xu T*, Li C*, Bao Q*. Molecular Mechanism of the β-Lactamase Mediated β-Lactam Antibiotic Resistance of Pseudomonas aeruginosa Isolated From a Chinese Teaching Hospital. Front Microbiol. 2022 Apr 28;13:855961. doi: 10.3389/fmicb.2022.855961. eCollection 2022.
13. Zhou K, Liang J, Dong X, Zhang P, Feng C, Shi W, Gao M, Li Q, Zhang X, Lu J, Lin X, Li K, Zhang H, Zhu M*, Bao Q*. Identification and Characterization of a Novel Chromosomal Aminoglycoside 2'-N-Acetyltransferase, AAC(2')-If, From an Isolate of a Novel Providencia Species, Providencia wenzhouensis R33. Front Microbiol. 2021 Nov 19;12:711037. doi: 10.3389/fmicb.2021.711037. eCollection 2021.
14. Dong X, Zhang P, Zhou K, Liang J, Li Q, Zhang X, Zhou D, Lu W, Sun Z, Liu H, Lu J, Lin X, Li K, Xu T, Zhang H, Zhu M*, Bao Q*. Characterization and identification of SFDC-1, a novel AmpC-type β-lactamase in Serratia fonticola. Environ Microbiol. 2021 Jul 5. doi: 10.1111/1462-2920.15663. Online ahead of print.
15. Lu W, Li K, Huang J, Sun Z, Li A, Liu H, Zhou D, Lin H, Zhang X, Li Q, Lu J, Lin X, Li P, Zhang H, Xu T, Bao Q*. Identification and characteristics of a novel aminoglycoside phosphotransferase, APH(3')-IId, from an MDR clinical isolate of Brucella intermedia. J Antimicrob Chemother. 2021 Jul 30:dkab272. doi: 10.1093/jac/dkab272.
16. Sun Z, Zhang X, Zhou D, Zhou K, Li Q, Lin H, Lu W, Liu H, Lu J, Lin X, Li K, Xu T, Zhu M, Bao Q*, Zhang H*. Identification of Three Clf-Sdr Subfamily Proteins in Staphylococcus warneri, and Comparative Genomics Analysis of a Locus Encoding CWA Proteins in Staphylococcus Species. Front Microbiol. 2021 Jul 29;12:691087. doi: 10.3389/fmicb.2021.691087. eCollection 2021.
17. Qian C, Liu H, Cao J, Ji Y, Lu W, Lu J, Li A, Zhu X, Shen K, Xu H, Chen Q, Zhou W, Lu H, Lin H, Zhang X, Li Q, Lin X, Li K, Xu T, Zhu M, Bao Q*, Zhang H*. Identification of floR Variants Associated With a Novel Tn4371-Like Integrative and Conjugative Element in Clinical Pseudomonas aeruginosa Isolates. Front Cell Infect Microbiol. 2021 Jun 21;11:685068. doi: 10.3389/fcimb.2021.685068. eCollection 2021.
18. Zhang X, Li Q, Lin H, Zhou W, Qian C, Sun Z, Lin L, Liu H, Lu J, Lin X, Li K, Xu T, Zhang H*, Li C*, Bao Q*. High-Level Aminoglycoside Resistance in Human Clinical Klebsiella pneumoniae Complex Isolates and Characteristics of armA-Carrying IncHI5 Plasmids. Front Microbiol. 2021 Apr 7;12:636396. doi: 10.3389/fmicb.2021.636396. eCollection 2021.
19. Lin X, Lu J, Qian C, Lin H, Li Q, Zhang X, Liu H, Sun Z, Zhou D, Lu W, Zhu M, Zhang H, Xu T, Li K, Bao Q*, Lin L*. Molecular and Functional Characterization of a Novel Plasmid-Borne bla NDM-Like Gene, bla AFM-1, in a Clinical Strain of Aeromonas hydrophila. Infect Drug Resist. 2021 Apr 22;14:1613-1622. doi: 10.2147/IDR.S297419. eCollection 2021.
20. Wu C, Zhang X, Liang J, Li Q, Lin H, Lin C, Liu H, Zhou D, Lu W, Sun Z, Lin X, Zhang H, Li K, Xu T, Bao Q*, Lu J*. Characterization of florfenicol resistance genes in the coagulase-negative Staphylococcus (CoNS) isolates and genomic features of a multidrug-resistant Staphylococcus lentus strain H29. Antimicrob Resist Infect Control. 2021 Jan 7;10(1):9. doi: 10.1186/s13756-020-00869-5.
21. Qian C, Zhu X, Lu J, Shen K, Chen Q, Zhou W, Liu H, Lu W, Zhou D, Sun Z, Lin X, Li K, Bao Q*, Xu T*, Lu S*. Characterization of an IncR Plasmid with Two Copies of ISCR-Linked qnrB6 from ST968 Klebsiella pneumoniae. Int J Genomics. 2020 Nov 24;2020:3484328. doi: 10.1155/2020/3484328. eCollection 2020.
22. Zhu X, Li P, Qian C, Liu H, Lin H, Zhang X, Li Q, Lu J, Lin X, Xu T, Zhang H, Hu Y, Bao Q*, Li K*. Prevalence of aminoglycoside resistance genes and molecular characterization of a novel gene, aac(3)-IIg, among clinical isolates of the Enterobacter cloacae complex from a Chinese teaching hospital. Antimicrob Agents Chemother. 20 August 2020, 64:e00852-20. https://doi.org/10.1128/AAC.
23. Danying Zhou, Zhewei Sun, Junwan Lu, Hongmao Liu, Wei Lu, Hailong Lin, Xueya Zhang, Qiaoling Li, Wangxiao Zhou, Xinyi Zhu, Haili Xu, Xi Lin, Hailin Zhang, Teng Xu*, Kewei Li* and Qiyu Bao*. Characterization of a Novel Chromosomal Class C b-Lactamase, YOC-1, and Comparative Genomics Analysis of a Multidrug Resistance Plasmid in Yokenella regensburgei W13. Front. Microbiol. 2020. 11:2021. doi: 10.3389/fmicb.2020.02021.
24. Zhewei Sun, Danying Zhou, Xueya Zhang, Qiaoling Li, Hailong Lin, Wei Lu, Hongmao Liu, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Qiyu Bao* and Hailin Zhang*. Determining the Genetic Characteristics of Resistance and Virulence of the “Epidermidis Cluster Group” Through Pan-Genome Analysis. Front. Cell. Infect. Microbiol. 2020. 10:274. doi: 10.3389/fcimb.2020.00274.
25. Peizhen Li, Tingyuan Zhu, Danying Zhou, Wei Lu, Hongmao Liu, Zhewei Sun, Jun Ying, Junwan Lu, Xi Lin, Kewei Li, Jianchao Ying, Qiyu Bao* and Teng Xu*. Analysis of Resistance to Florfenicol and the Related Mechanism of Dissemination in Different Animal-Derived Bacteria. Front. Cell. Infect. Microbiol. 2020. 10:369.doi: 10.3389/fcimb.2020.00369.
26. Tingyuan Zhu, Suzhen Liu, Yuanyuan Ying, Lei Xu, Yabo Liu, Junjie Jin, Jun Ying, Junwan Lu, Xi Lin, Kewei Li, Teng Xu*, Qiyu Bao*, Peizhen Li*. Genomic and functional characterization of fecal sample strains of Proteus cibarius carrying two floR antibiotic resistance genes and a multiresistance plasmid-encoded cfr gene. Comparative Immunology, Microbiology and Infectious Diseases. 2020.101427, https://doi.org/10.1016/j.cimid.2020.
27. Jianchao Ying, Jun Ye, Teng Xu, Qian Wang, Qiyu Bao* and Aifang Li*. Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution. International Journal of Genomics. Dec. 18, 2019, Article ID 8987436, doi.org/10.1155/2019/8987436.
28. Jian Wang, Teng Xu, Jun Ying, Wangxiao Zhou, Qianqian Chen, Changrui Qian, Xinyi Zhu, Kai Shen, Peizhen Li, Kewei Li, Qiyu Bao,* and Junwan Lu*. PAU-1, a novel plasmid-encoded Ambler class A β-lactamase identified in a clinical Pseudomonas aeruginosa isolate. Infect Drug Resist. 2019 Dec 5;12:3827-3834. doi: 10.2147/IDR.S225288. eCollection 2019.
29. Yabo Liu, Fei Wu, Qing Chen, Yuanyuan Ying, Yi Jiang, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Qiyu Bao*, Liyan Ni*. Comparative genomics analysis of Raoultella planticola S25 isolated from duck in China, with florfenicol resistance. Comp Immunol Microbiol Infect Dis 10s. 68 (2020) 101398, doi.org/10.1016/j.cimid.2019.101398.
30. Qianqian Chen, Wangxiao Zhou, Changrui Qian, Kai Shen, Xinyi Zhu, Danying Zhou, Zhewei Sun, Wei Lu, Hongmao Liu, Kewei Li, Teng Xu, Qiyu Bao* and Junwan Lu*. OXA-830, a Novel Chromosomally Encoded Extended-Spectrum Class D β-Lactamase in Aeromonas simiae. Front Microbiol.2019 Nov 26; 10:2732. doi: 10.3389/fmicb.2019.02732.
31. Wangxiao Zhou, Qianqian Chen, Changrui Qian, Kai Shen, Xinyi Zhu, Danying Zhou, Wei Lu, Zhewei Sun, Hongmao Liu, Kewei Li, Teng Xu, Qiyu Bao* and Junwan Lu*. In Vitro Susceptibility and Florfenicol Resistance in Citrobacter Isolates and Whole-Genome Analysis of Multidrug-Resistant Citrobacter freundii. Int J Genomics. November 19, 2019, Article ID 7191935, doi.org/10.1155/2019/7191935.
32. Ying Y, Wu F, Wu C, Jiang Y, Yin M, Zhou W, Zhu X, Cheng C, Zhu L, Li K, Lu J, Xu T, Bao Q*. Florfenicol Resistance in Enterobacteriaceae and Whole-Genome Sequence Analysis of Florfenicol-Resistant Leclercia adecarboxylata Strain R25. Int J Genomics. 2019 Oct 1;2019:9828504. doi: 10.1155/2019/9828504. eCollection 2019.
33. Wu F, Ying Y, Yin M, Jiang Y, Wu C, Qian C, Chen Q, Shen K, Cheng C, Zhu L, Li K, Xu T, Bao Q*, Lu J*. Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit. Int J Genomics. 2019 Aug 18;2019:5459190. doi: 10.1155/2019/5459190.
34. Hou L, Debru A, Chen Q, Bao Q*, Li K*. AmrZ Regulates Swarming Motility Through Cyclic di-GMP-Dependent Motility Inhibition and Controlling Pel Polysaccharide Pro4duction in Pseudomonas aeruginosa PA14. Front Microbiol. 2019 Aug 14;10:1847. doi: 10.3389/fmicb.2019.01847.
35. Yin M, Jiang Y, Qian C, Wu F, Ying Y, Wu C, Li P, Ying J, Li K, Xu T, Bao Q*, Sun C*. Molecular characteristics and comparative genomics analysis of a clinical Enterococcus casseliflavus with a resistance plasmid. Infect Drug Resist. 2018 Nov 5; 11:2159-2167. doi: 10.2147/IDR.S180254. eCollection 2018.
36. Lu J, Zhang J, Xu L, Liu Y, Li P, Zhu T, Cheng C, Lu S, Xu T, Yi H, Li K, Zhou W, Li P, Ni L, Bao Q*. Spread of the florfenicol resistance floR gene among clinical Klebsiella pneumoniae isolates in China. Antimicrob Resist Infect Control. 2018 Nov 1; 7:127. doi: 10.1186/s13756-018-0415-0. eCollection 2018.
37. Li P, Shen K, Zhang Y, Ying J, Zhu T, Liu Y, Xu L, Lin C, Zhang K, Li P, Lu J, Li K, Yi H, Bao Q*, Xu T*. Characterization of a Novel blaKLUC Variant With Reduced β-Lactam Resistance From an IncA/C Group Plasmid in a Clinical Klebsiella pneumoniae Isolate. Front Microbiol. 2018 Aug 15; 9:1908. doi: 10.3389/fmicb.2018.01908. eCollection 2018.
38. Xu T, Wang J, Ying J, Zhu T, Liu Y, Xu L, Li P, Li P, Ying J, Li K, Yi H, Lu J, Hu Y, Zhou T, Bao Q*. Characterisation of a class 1 integron associated with the formation of quadruple blaGES-5 cassettes from an IncP-1β group plasmid in Pseudomonas aeruginosa. Int J Antimicrob Agents. 2018 Oct; 52(4):485-491. doi: 10.1016/j.ijantimicag.2018.07.002.
39. Xu L, Yin M, Zhu T, Liu Y, Ying Y, Lu J, Lin C, Ying J, Xu T, Ni L, Bao Q*, Lu S. Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate of Pantoea vagansPV989. Int J Genomics. 2018 May 10; 2018:1242819. doi: 10.1155/2018/1242819. eCollection 2018.
40. Li K, Yang G, Debru AB, Li P, Zong L, Li P, Xu T, Wu W*, Jin S*, Bao Q*. SuhB Regulates the Motile-Sessile Switch in Pseudomonas aeruginosa through the Gac/Rsm Pathway and c-di-GMP Signaling. Front Microbiol. 2017 Jun 8;8:1045. doi: 10.3389/fmicb.2017.01045. eCollection 2017.
41. Zhu M, Yang G, Li A, Zong L, Dong Z, Lu J, Zhang K, Cheng C, Chang Q, Wu X, Ying J, Li X, Ding L, Zheng H, Yu J, Ying J, Xu T, Yi H, Li P, Li K, Wu S, Bao Q*, Wang J*. Identification and molecular characterization of Escherichia coli blaSHV genes in a Chinese teaching hospital. Gene. 2017 Feb 5;600:29-35.
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43. Li P, Ying J, Yang G, Li A, Wang J, Lu J, Wang J, Xu T, Yi H, Li K, Jin S, Bao Q*, Zhang K*. Structure-Function Analysis of the Transmembrane Protein AmpG from Pseudomonas aeruginosa. PLoS One. 2016 Dec 13;11(12):e0168060.
44. Ying J, Wang J, Ji H, Lin C, Pan R, Zhou L, Song Y, Zhang E, Ren P, Chen J, Liu Q, Xu T, Yi H, Li J, Bao Q*, Hu Y*, Li P*. Transcriptome analysis of phycocyanin inhibitory effects on SKOV-3 cell proliferation. Gene. 2016 Jul 1;585(1):58-64.
45. Pan R, Lu R, Zhang Y, Zhu M, Zhu W, Yang R, Zhang E, Ying J, Xu T, Yi H, Li J, Shi M, Zhou L, Xu Z, Li P, Bao Q*. Spirulina phycocyanin induces differential protein expression and apoptosis in SKOV-3 cells. Int J Biol Macromol. 2015 Sep 26; 81:951-959. doi: 10.1016/j.ijbiomac.2015.09.039.
46. Ying J, Wu S, Zhang K, Wang Z, Zhu W, Zhu M, Zhang Y, Cheng C, Wang H, Tou H, Zhu C, Li P, Ying J, Xu T, Yi H, Li J, Ni L, Xu Z, Bao Q*, Lu J*. Comparative genomics analysis of pKF3-94 in Klebsiella pneumoniae reveals plasmid compatibility and horizontal gene transfer. Front Microbiol. 2015 Aug 18;6:831. doi: 10.3389/fmicb. 2015.00831. eCollection 2015.
47. Jianchao Ying, Huifeng Wang, Bokan Bao, Ying Zhang, Jinfang Zhang, Cheng Zhang, Aifang Li, Junwan Lu, Peizhen Li, Jun Ying, Qi Liu, Teng Xu, Huiguang Yi, Jinsong Li, Li Zhou, Tieli Zhou, Zuyuan Xu, Liyan Ni, Qiyu Bao*. Molecular Variation and Horizontal Gene Transfer of the Homocysteine Methyltransferase Gene mmuM and its Distribution in Clinical Pathogens. International Journal of Biological Sciences, 2015; 11(1): 11-21. doi: 10.7150/ijbs.10320.
48. Peizhen Li, Liang Zhao, Xiaomin Xu, Chenyang Xu, Chunlei Jin, Yi Xu, Jiaopeng Zhou, Ying Zhang, Kangfu Lei, Jun Ying, Ping Ren, Lei Yang, Ruowang Pan, Zuyuan Xu, Huifeng Wang, Qiyu Bao*, Li Ding*. Analysis of the promoter region of the RuBisCO gene of Arthrospira (Spirulina ) platensis. J Appl Phycol, 26(2) :199-207, 2014.
49. Huili W, Xiaokai Z, Meili L, Dahlgren RA, Wei C, Jaiopeng Z, Chengyang X, Chunlei J, Yi X, Xuedong W, Li D, Qiyu B*. Proteomic Analysis and qRT-PCR Verification of Temperature Response to Arthrospira (Spirulina) platensis. PLoS One. 2013 Dec 12;8(12):e83485.
50. XIAOKAI ZHAO,XUEDONG WANG,JIAOPENG ZHOU,BIAOBANG CHEN,AIBING ZENG,QIYU BAO* AND HUILI WANG*. Proteomic analysis and qRT-PCR verification of Arthrospira platensis strain YZ under dark stress. Phycologia, ,2013, 52 (6): 538–549.
51. Bai J, Liu Q, Yang Y, Wang J, Yan g Y, Li J, Li P, Li X, Xi Y, Ying J, Ren P, Yang L, Ni L, Wu J, Bao Q*, Zhou T*. Insights into the evolution of gene organization and multidrug resistance from Klebsiella pneumoniae plasmid pKF3-140. Gene. 2013 Apr 25; 519 (1): 60-6.
52. Wang H, Yang Y, Chen W, Ding L, Li P, Zhao X, Wang X, Li A, Bao Q*. Identification of differentially expressed proteins of Arthrospira (Spirulina) plantensis-YZ under salt-stress conditions by proteomics and qRT-PCR analysis. Proteome Sci. 2013 Jan 30;11(1):6.
53. Xu T, Ying J, Yao X, Song Y, Ma P, Bao B, Jiang W, Wu X, Tou H, Li P, Ren P, Fei J, Yang L, Liu Q, Xu Z, Zhou T, Ni L, Bao Q*. Identification and Characterization of Two Novel bla(KLUC) Resistance Genes through Large-Scale Resistance Plasmids Sequencing. PLoS One. 2012; 7(10): e47197.
54. Peizhen Li, Biaobang Chen, Zhijian Song, Yulong Song, Yanmei Yang, Ping Ma, Huifeng Wang, Jun Ying, Ping Ren, Lei Yang, Guohui Gao, Shouguang Jin, Qiyu Bao*, Hongjiang Yang*. Bioinformatic analysis of the Acinetobacter baumannii phage AB1 genome. Gene, 2012, 507: 125-134.
55. Yu T, Li J, Yang Y, Qi L, Chen B, Zhao F, Bao Q*, Wu J*.Codon usage patterns and adaptive evolution of marine unicellular cyanobacteria Synechococcus and Prochlorococcus. Mol Phylogenet Evol. 2012 Jan; 62(1):206-13.
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57. Fangqing Zhao, Jie Bai, Jinyu Wu, Jing Liu, Mingming Zhou, Huiguang Yi, Teng Xu, Wei Chen, Biaobang Chen, Meili Lin, Shengjie Gao, Tieli Zhou, Zuyuan Xu, Yuxin Niu and Qiyu Bao*. Sequencing and genetic variation of multidrug resistance plasmids in clinical samples. PlosOne. 2010, 5(4):e10141.(IF: 4.352)
58. Huiguang Yi, Yali Xi, Jing Liu, Junrong Wang, Jinyu Wu, Teng Xu, Wei Chen, Biaobang Chen, Meili Lin, Huan Wang, Mingming Zhou, Jinsong Li, Zuyuan Xu, Shouguang Jin, Qiyu Bao*. Sequence Analysis of pKF3-70 in Klebsiella pneumoniae: Probable Origin from R100-like Plasmid of Escherichia coli. PLoS One. 2010, 5 (1):e8601.
59. Guiming Liu, Jinyu Wu, Huanming Yang, Qiyu Bao*. Codon Usage Patterns in Corynebacterium glutamicum: Mutational Bias, Natural Selection and Amino Acid Conservation. Comp Funct Genomics. 2010; 2010:343569.
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62. JinyuWu, Tonghai Yu, Qiyu Bao*, and Fangqing Zhao*,Evidence of Extensive Homologous Recombination in the Core Genome of Rickettsia. Comp Funct Genomics. 2009:510270.
63. Jinyu Wu, Xiang Xu, Jian Xiao, Long Xu, Huiguang Yi, Shengjie Gao, Jing Liu, Qiyu Bao*, Fangqing Zhao* and Xiaokun Li* FlyPhy: a phylogenomic analysis platform for Drosophila genes and gene families. BMC Bioinformatics. 2009 Apr 25;10:123.
64. Xiang Xu, Jinyu Wu, Jian Xiao, Yi Tan, Qiyu Bao*, Fangqing Zhao* and Xiaokun Li*. PlasmoGF: an integrated system for comparative genomics and phylogenetic analysis of Plasmodium gene families. Bioinformatics. 2008, 24 (9) : 1217-20.
65. Wu J, Bai J, Bao Q*, Zhao F*. Lineage-Specific Domain Fusion in the Evolution of Purine Nucleotide Cyclases in Cyanobacteria. J Mol Evol. 2008, 67(1):85-94.
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67. Jinyu Wu, Shengqin Wang, Jie Bai, Jia Qu, Jinyu Wu, Shengqin Wang, Jie Bai, Liang Shi, Dong Li, Zuyuan Xu, Yuxin Niu, Jianxin Lu, Qiyu Bao*. ArchaeaTF: An integrated database of putative transcription factors in Archaea. Genomics. 2008,91(1):102-107.
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获奖情况:
1. 中国科学院院长特别奖,中国科学院,2002.12,第一。
2. 螺旋藻抗逆相关功能基因组研究,浙江省科学技术进步奖三等奖,浙江省人民政府,2017年,第一。
3.疾病相关细菌耐药性基因检测芯片的研制,浙江省科学技术进步奖三等奖,浙江省人民政府,2015年,第一。
4. 疾病相关细菌耐药性基因检测芯片的研制,浙江省医药卫生科技奖二等奖,浙江省卫生厅,2012年,第一。
5. 疾病相关细菌耐药性基因检测芯片的研制,温州市科技进步奖三等奖,温州市人民政府,证书编号:WK20129401,2012.12,第一。
6. 温州地区小二喉乳头状瘤病因学及临床治疗研究,浙江省科学技术进步奖三 等奖,浙江省人民政府,证书编号:0503256,2005.12, 第二。
7.肝病实验诊断项目分类方法的研究,浙江省科学技术进步奖三等奖,浙江省人民政府,证书编号:0203113-2,2002.12,第二。
8.小儿腹泻病原及其分子生物学研究,浙江省科学技术进步奖三等奖,浙江省人民政府,证书编号:994253,1999.12,第一。